SLC6A1-AS1

Across TCGA pan-cancer cohorts, SLC6A1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SLC6A1-AS1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SLC6A1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC6A1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and THCA show a favorable association.

STAD, UVM, and DLBC are the cancer types where SLC6A1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Quartile	All	0.239	0.427	.004	52	view →
UVM	DFS	Tertile	II,III,IV	0.422	0.653	.012	45	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
LUAD	DFS	Median	III,IV	0.662	0.278	<.001	31	view →
BRCA	OS	Median	All	0.514	0.637	.004	21	view →
THCA	DFS	Quartile	All	0.957	0.808	.002	12	view →
UCEC	DFS	Tertile	All	0.860	0.905	.013	12	view →
SARC	OS	Median	All	0.891	0.781	.013	11	view →
LGG	OS	Tertile	All	0.665	0.410	.006	10	view →
READ	DFS	Quartile	IV	0.122	0.668	<.001	9	view →
GBM	OS	Quartile	All	0.593	0.292	.008	9	view →
COAD	OS	Tertile	All	0.693	0.838	.017	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SLC6A1-AS1–STAD (DFS)

Open the STAD breakdown →