SLC5A7

Across TCGA pan-cancer cohorts, SLC5A7 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC5A7 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC5A7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC5A7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, GBM, and PDAC are the cancer types where SLC5A7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.983	0.836	.028	6	view →
GBM	OS	Median	All	0.602	0.933	.006	6	view →
PDAC	OS	Median	IV	0.962	0.381	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC5A7–UCEC (DFS)

Open the UCEC breakdown →