SLC5A7

Across TCGA patient cohorts, SLC5A7 mutation is significantly associated with the RNA expression of many other genes, with 2,598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A7-associated genes across cancer lineages are UBE2S, MRPS15, and NUSAP1. Each is linked with SLC5A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A7-to-partner and partner-to-SLC5A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2S grouped by SLC5A7-low versus SLC5A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A7→partner) and Y-score (partner→SLC5A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2S →	+0.716	+2.305	<.001	<.001	3	3
UCEC	MRPS15 →	+0.451	+2.021	<.001	<.001	3	3
UCEC	NUSAP1 →	+0.519	+1.546	.006	.008	3	3
UCEC	TACC3 →	+0.507	+2.273	.002	<.001	3	3
UCEC	CEP55 →	+0.534	+1.874	.005	.002	3	3
UCEC	NABP2 →	+0.294	+2.016	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,598 associations by consensus.

UBE2S by SLC5A7 expression — UCEC

Explore this box plot interactively →