SLC5A7

Across TCGA cell cohorts, SLC5A7 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC5A7-associated genes across cancer lineages are OR2A14, GFRA4, and TSHB. Each is linked with SLC5A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A7-to-partner and partner-to-SLC5A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A14 grouped by SLC5A7-low versus SLC5A7-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A7→partner) and Y-score (partner→SLC5A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR2A14 →	+0.054	+4.472	<.001	.004	3	2
BLOOD_Leukemia	GFRA4 →	+0.314	+4.409	<.001	.005	3	1
BLOOD_Leukemia	TSHB →	+0.261	+4.276	<.001	.007	3	1
BLOOD_Leukemia	TMEM132C →	+1.109	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR1G1 →	+0.039	+4.705	.008	.003	3	1
BLOOD_Leukemia	FIGLA →	+0.027	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

OR2A14 by SLC5A7 expression — CNS

Explore this box plot interactively →