SLC5A7

Across TCGA cell cohorts, SLC5A7 mutation is significantly associated with the mutation status of many other genes, with 3,691 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A7-associated genes across cancer lineages are ANK2, ANKRD13B, and ZFP64. Each is linked with SLC5A7 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC5A7-to-partner and partner-to-SLC5A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANK2 grouped by SLC5A7-low versus SLC5A7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A7→partner) and Y-score (partner→SLC5A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ANK2 →	+2.058	+2.799	.006	.006	1	5
LARGE_INTESTINE	ANKRD13B →	+2.471	+2.369	.005	.005	1	5
OVARY	ZFP64 →	+4.930	+3.977	.001	.001	1	4
BLOOD_Lymphoma	IQSEC2 →	+4.014	+4.969	.008	.008	1	4
LARGE_INTESTINE	OGDH →	+2.208	+2.208	.009	.009	1	4
BLOOD_Leukemia	DNM1 →	+3.479	+4.932	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

ANK2 by SLC5A7 expression — SKIN

Explore this box plot interactively →