SLC5A4-AS1

Across TCGA pan-cancer cohorts, SLC5A4-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SLC5A4-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SLC5A4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC5A4-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUSC show a favorable association.

LIHC, THCA, and UCEC are the cancer types where SLC5A4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.673	0.835	.002	47	view →
THCA	OS	Tertile	IV	0.582	0.910	.008	35	view →
UCEC	OS	Quartile	All	0.824	0.914	.004	32	view →
UCS	DFS	Tertile	IV	0.936	0.429	.017	30	view →
ACC	OS	Quartile	All	0.359	0.810	.007	19	view →
CESC	DFS	Tertile	All	0.719	0.858	<.001	18	view →
BLCA	DFS	Quartile	All	0.514	0.654	.011	18	view →
LUSC	OS	Median	All	0.816	0.733	.005	15	view →
READ	OS	Quartile	III,IV	0.911	0.501	.015	15	view →
SKCM	OS	Median	All	0.834	0.733	.008	14	view →
LUAD	OS	Tertile	All	0.755	0.887	.004	14	view →
CHOL	DFS	Quartile	II,III,IV	0.095	0.412	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SLC5A4-AS1–LIHC (OS)

Open the LIHC breakdown →