Across TCGA patient cohorts, SLC5A3 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A3-associated genes across cancer lineages are PDCD4, ATM, and ACC1. Each is linked with SLC5A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A3-to-partner and partner-to-SLC5A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A3→partner) and Y-score (partner→SLC5A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.401	-1.222	.002	.011	3	3
UCEC	ATM →	-0.462	-2.723	<.001	<.001	3	3
UCEC	ACC1 →	+0.290	+1.920	.005	.008	3	2
COAD	Rad50 →	-0.246	-3.296	.006	.009	3	2
UCEC	ASNS →	+0.240	+1.222	.019	.032	3	2
UCEC	C-Raf →	+0.146	+1.716	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

SLC5A3 survival (RNA) · tumor vs normal (RNA) · all SLC5A3 data types