Across TCGA cell cohorts, SLC5A3 mutation is significantly associated with the mutation status of many other genes, with 3,516 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A3-associated genes across cancer lineages are ELF1, RALBP1, and SHANK3. Each is linked with SLC5A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC5A3-to-partner and partner-to-SLC5A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A3→partner) and Y-score (partner→SLC5A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELF1 →	+3.459	+4.954	<.001	<.001	1	4
LARGE_INTESTINE	RALBP1 →	+3.196	+4.793	<.001	<.001	1	4
BLOOD_Leukemia	SHANK3 →	+3.145	+3.932	.004	.004	1	3
BLOOD_Leukemia	OR52R1 →	+4.560	+4.309	.007	.007	1	3
LARGE_INTESTINE	LCTL →	+3.459	+3.459	.006	.006	1	3
BLOOD_Leukemia	IPO4 →	+3.338	+4.083	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,516 associations by consensus.

Exploration

SLC5A3 survival (RNA) · tumor vs normal (RNA) · all SLC5A3 data types