SLC5A2

Across TCGA patient cohorts, SLC5A2 mutation is significantly associated with the RNA expression of many other genes, with 2,346 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A2-associated genes across cancer lineages are SLBP, ZBTB8OS, and TLE6. Each is linked with SLC5A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A2-to-partner and partner-to-SLC5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLBP grouped by SLC5A2-low versus SLC5A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A2→partner) and Y-score (partner→SLC5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLBP →	+0.444	+2.732	.003	.003	3	3
UCEC	ZBTB8OS →	+0.299	+1.748	.001	.002	3	3
COAD	TLE6 →	+0.552	+3.727	.001	<.001	3	3
UCEC	TIGD2 →	+0.610	+1.759	<.001	.002	3	3
UCEC	RPS27L →	+0.535	+2.392	<.001	<.001	3	3
UCEC	HMX3 →	+0.389	+1.345	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,346 associations by consensus.

SLBP by SLC5A2 expression — UCEC

Explore this box plot interactively →