SLC5A12

Across TCGA patient cohorts, SLC5A12 mutation is significantly associated with the RNA expression of many other genes, with 2,251 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A12-associated genes across cancer lineages are OSTCP6, OR10A7, and TAF9. Each is linked with SLC5A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A12-to-partner and partner-to-SLC5A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OSTCP6 grouped by SLC5A12-low versus SLC5A12-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A12→partner) and Y-score (partner→SLC5A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OSTCP6 →	+0.183	+2.816	<.001	.007	3	3
LIHC	OR10A7 →	+0.053	+4.758	<.001	.006	3	3
UCEC	TAF9 →	+0.533	+2.928	<.001	<.001	3	3
UCEC	DONSON →	+0.409	+1.934	.002	.002	3	3
UCEC	RPP14 →	+0.278	+1.856	.005	.004	3	3
UCEC	H2AZ1 →	+0.474	+1.748	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,251 associations by consensus.

OSTCP6 by SLC5A12 expression — HNSC

Explore this box plot interactively →