SLC5A12

Across TCGA cell cohorts, SLC5A12 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SLC5A12-associated genes across cancer lineages are DAOA, C14orf177, and ODF4. Each is linked with SLC5A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A12-to-partner and partner-to-SLC5A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAOA grouped by SLC5A12-low versus SLC5A12-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A12→partner) and Y-score (partner→SLC5A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAOA →	+0.046	+4.022	<.001	.006	3	2
BLOOD_Leukemia	C14orf177 →	+0.069	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ODF4 →	+0.043	+4.922	<.001	.009	3	1
STOMACH	GZMH →	+0.037	+4.285	<.001	.007	3	1
STOMACH	LUZP4 →	+0.011	+4.432	<.001	.003	3	1
STOMACH	VN1R3 →	+0.020	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

DAOA by SLC5A12 expression — LARGE_INTESTINE

Explore this box plot interactively →