SLC5A10

Across TCGA patient cohorts, SLC5A10 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A10-associated genes across cancer lineages are PI3K-p85, Cyclin-E2, and ERK2. Each is linked with SLC5A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A10-to-partner and partner-to-SLC5A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PI3K-p85 grouped by SLC5A10-low versus SLC5A10-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A10→partner) and Y-score (partner→SLC5A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PI3K-p85 →	+0.190	+3.000	.029	.034	3	2
STAD	Cyclin-E2 →	+0.151	+3.021	.032	.018	3	2
UCEC	ERK2 →	+0.231	+2.247	.001	.001	3	2
UCEC	INPP4B →	-0.289	-3.700	.015	.001	3	2
UCEC	Ku80 →	+0.387	+2.750	<.001	<.001	3	2
UCEC	Rab25 →	-0.412	-2.736	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

PI3K-p85 by SLC5A10 expression — STAD

Explore this box plot interactively →