SLC5A10

Across TCGA cell cohorts, SLC5A10 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A10-associated genes across cancer lineages are ADCY4, LYVE1, and SLC22A3. Each is linked with SLC5A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A10-to-partner and partner-to-SLC5A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADCY4 grouped by SLC5A10-low versus SLC5A10-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A10→partner) and Y-score (partner→SLC5A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ADCY4 →	+0.429	+3.469	<.001	.004	3	1
SKIN	LYVE1 →	+0.087	+3.925	.003	.001	3	1
SKIN	SLC22A3 →	+0.311	+3.967	.008	<.001	3	1
SKIN	PPEF2 →	+0.018	+3.292	<.001	.007	3	1
SKIN	C5orf52 →	+0.031	+3.678	<.001	.001	3	1
LARGE_INTESTINE	CHST8 →	+0.119	+3.643	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

ADCY4 by SLC5A10 expression — SKIN

Explore this box plot interactively →