SLC5A1

Across TCGA cell cohorts, SLC5A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,229 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A1-associated GO terms across cancer lineages are Glucoside transport, Positive regulation of chromatin binding, and Serotonin secretion. Each is linked with SLC5A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC5A1-to-partner and partner-to-SLC5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glucoside transport grouped by SLC5A1-low versus SLC5A1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A1→partner) and Y-score (partner→SLC5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Glucoside transport →	-0.295	-0.638	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Positive regulation of chromatin binding →	+0.133	+0.302	<.001	.004	3	6
LUNG_SCLC	Serotonin secretion →	+1.065	+0.517	.001	.005	3	6
LUNG_SCLC	Regulation of potassium ion import →	+0.178	+0.791	.002	.001	3	6
LARGE_INTESTINE	Positive regulation of potassium ion import across plasma membrane →	+0.152	+1.359	<.001	<.001	3	6
LUNG_SCLC	Desmosome maintenance →	+0.904	+0.717	.003	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,229 associations by consensus.

Glucoside transport by SLC5A1 expression — LUNG_SCLC

Explore this box plot interactively →