SLC52A3

Across TCGA cell cohorts, SLC52A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,294 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SLC52A3-associated GO terms across cancer lineages are Rho protein signal transduction, Cellular response to indole-3-methanol, and Maintenance of blood-brain barrier. Each is linked with SLC52A3 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC52A3-to-partner and partner-to-SLC52A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rho protein signal transduction grouped by SLC52A3-low versus SLC52A3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A3→partner) and Y-score (partner→SLC52A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Rho protein signal transduction →	+0.098	+1.489	.002	<.001	3	11
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.218	+2.754	<.001	<.001	2	12
PANCREAS	Maintenance of blood-brain barrier →	+0.225	+1.669	<.001	.001	3	11
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.319	+2.221	<.001	<.001	3	10
OVARY	T cell mediated cytotoxicity →	+0.237	+1.520	.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of iron ion transport →	+1.897	+2.048	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

Rho protein signal transduction by SLC52A3 expression — OESOPHAGUS

Explore this box plot interactively →