Across TCGA patient cohorts, SLC52A2 mutation is significantly associated with the RNA expression of many other genes, with 1,362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC52A2-associated genes across cancer lineages are RNU1-57P, SNORD53, and ZDHHC7. Each is linked with SLC52A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC52A2-to-partner and partner-to-SLC52A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A2→partner) and Y-score (partner→SLC52A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU1-57P →	+0.406	+7.930	<.001	.008	3	2
UCEC	SNORD53 →	+0.523	+2.132	.004	.003	3	2
UCEC	ZDHHC7 →	+0.675	+3.906	<.001	<.001	3	2
UCEC	KLC2 →	+0.410	+3.467	.009	.002	3	2
SKCM	ARHGEF38-IT1 →	+0.054	+3.132	.002	.003	3	2
UCEC	NAPA →	+0.450	+2.633	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,362 associations by consensus.

Exploration

SLC52A2 survival (RNA) · tumor vs normal (RNA) · all SLC52A2 data types