Across TCGA patient cohorts, SLC52A2 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC52A2-associated genes across cancer lineages are Erythrocytes, Endothelial cells, and lymphatic Endothelial cells. Each is linked with SLC52A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC52A2-to-partner and partner-to-SLC52A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A2→partner) and Y-score (partner→SLC52A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.027	+3.010	.013	.019	3	2
UCEC	Endothelial cells →	-0.042	-2.072	.010	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.660	.009	.001	3	1
UCEC	Macrophages M2 →	+0.014	+3.483	.001	.002	3	1
UCEC	mv Endothelial cells →	-0.030	-3.584	.003	.002	3	1
UCEC	pDC →	+0.056	+2.126	.008	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

SLC52A2 survival (RNA) · tumor vs normal (RNA) · all SLC52A2 data types