SLC52A1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC52A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,143 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible SLC52A1-associated GO terms across cancer lineages are Positive regulation of protein catabolic process, Vesicle targeting, rough ER to cis-Golgi, and Regulation of myoblast fusion. Each is linked with SLC52A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC52A1-to-partner and partner-to-SLC52A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein catabolic process grouped by SLC52A1-low versus SLC52A1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A1→partner) and Y-score (partner→SLC52A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of protein catabolic process →+0.058+1.129<.001<.001310
OVARYVesicle targeting, rough ER to cis-Golgi →+0.065+0.423.003.006310
OESOPHAGUSRegulation of myoblast fusion →+0.131+2.233<.001<.00139
OESOPHAGUSNegative regulation of myoblast fusion →+0.128+1.908<.001<.00139
OESOPHAGUSNegative regulation of syncytium formation by plasma membrane fusion →+0.128+1.908<.001<.00139
OESOPHAGUSRegulation of syncytium formation by plasma membrane fusion →+0.122+2.159<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,143 associations by consensus.

Positive regulation of protein catabolic process by SLC52A1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of protein catabolic process in SLC52A1-low vs SLC52A1-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration