SLC51A

Across TCGA cell cohorts, SLC51A mutation is significantly associated with the mutation status of many other genes, with 1,326 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC51A-associated genes across cancer lineages are KEAP1, GGT5, and PIKFYVE. Each is linked with SLC51A in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC51A-to-partner and partner-to-SLC51A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KEAP1 grouped by SLC51A-low versus SLC51A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC51A→partner) and Y-score (partner→SLC51A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KEAP1 →	+3.087	+4.392	.005	.005	1	2
LARGE_INTESTINE	GGT5 →	+3.672	+4.799	.002	.002	1	2
BLOOD_Leukemia	PIKFYVE →	+3.479	+4.932	.002	.002	1	2
BLOOD_Leukemia	OPRD1 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	CNR1 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	ADGB →	+3.672	+5.083	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,326 associations by consensus.

KEAP1 by SLC51A expression — LARGE_INTESTINE

Explore this box plot interactively →