SLC50A1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC50A1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC50A1-associated genes across cancer lineages are ACC1 and cIAP. Each is linked with SLC50A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC50A1-to-partner and partner-to-SLC50A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by SLC50A1-low versus SLC50A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC50A1→partner) and Y-score (partner→SLC50A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECACC1 →+0.737+2.820<.001.03531
UCECcIAP →+0.240+2.833.004.03531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ACC1 by SLC50A1 expression — UCEC

Box plot of ACC1 in SLC50A1-low vs SLC50A1-high samples in UCEC.

Explore this box plot interactively →

Exploration