SLC4A8

Across TCGA patient cohorts, SLC4A8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,720 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC4A8-associated genes across cancer lineages are SEZ6L, RASD2, and SYNGR1. Each is linked with SLC4A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A8-to-partner and partner-to-SLC4A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC4A8 versus SEZ6L in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A8→partner) and Y-score (partner→SLC4A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEZ6L →	+1.688	+0.302	.003	.004	3	1
GBM	RASD2 →	+0.555	+0.256	.001	.002	3	1
GBM	SYNGR1 →	+0.950	+0.365	<.001	<.001	3	1
GBM	PNPLA5 →	+0.254	+0.240	<.001	.005	3	1
GBM	CACNA1I →	+0.423	+0.183	.002	.005	3	1
GBM	PVALB →	+1.170	+0.337	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,720 associations by consensus.

SLC4A8 vs SEZ6L — GBM

Explore this scatter interactively →