SLC4A7

Across TCGA pan-cancer cohorts, SLC4A7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC4A7 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC4A7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC4A7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and GBM are the cancer types where SLC4A7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	1.000	0.314	.042	12	view →
LSCC	OS	Quartile	All	0.997	0.777	.006	11	view →
GBM	DFS	Tertile	All	0.273	0.466	.002	9	view →
CCRCC	OS	Median	III,IV	0.524	0.789	.012	5	view →
HNSC	OS	Median	III,IV	0.786	0.574	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC4A7–UCEC (OS)

Open the UCEC breakdown →