SLC4A7

Across TCGA patient cohorts, SLC4A7 mutation is significantly associated with the RNA expression of many other genes, with 5,328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A7-associated genes across cancer lineages are RNU6-1213P, IGHD5-12, and RNVU1-33. Each is linked with SLC4A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A7-to-partner and partner-to-SLC4A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by SLC4A7-low versus SLC4A7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A7→partner) and Y-score (partner→SLC4A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1213P →	+0.298	+5.649	<.001	.001	3	3
READ	IGHD5-12 →	+1.742	+5.421	<.001	.005	3	3
CESC	RNVU1-33 →	+0.222	+3.816	<.001	.007	3	3
UCEC	JOSD1 →	+0.384	+1.788	<.001	<.001	3	3
COAD	VRK1 →	+0.549	+3.342	.002	.005	3	3
SKCM	NCAPG →	+0.965	+2.706	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,328 associations by consensus.

RNU6-1213P by SLC4A7 expression — BRCA

Explore this box plot interactively →