SLC4A7

Across TCGA cell cohorts, SLC4A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,906 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC4A7-associated GO terms across cancer lineages are Microtubule polymerization, Microtubule polymerization or depolymerization, and Regulation of smoothened signaling pathway. Each is linked with SLC4A7 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC4A7-to-partner and partner-to-SLC4A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by SLC4A7-low versus SLC4A7-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A7→partner) and Y-score (partner→SLC4A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule polymerization →	+0.126	+1.045	<.001	<.001	3	15
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.111	+1.162	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of smoothened signaling pathway →	+0.032	+1.246	.002	.006	3	12
LUNG_NSCLC_LUSC	Protein localization to cilium →	+0.071	+1.235	.005	.007	3	12
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.112	+1.824	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.115	+1.707	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,906 associations by consensus.

Microtubule polymerization by SLC4A7 expression — LARGE_INTESTINE

Explore this box plot interactively →