SLC4A7

Across TCGA cell cohorts, SLC4A7 mutation is significantly associated with the RNA expression of many other genes, with 630 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC4A7-associated genes across cancer lineages are PARD6A, CRACD, and LANCL1. Each is linked with SLC4A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A7-to-partner and partner-to-SLC4A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PARD6A grouped by SLC4A7-low versus SLC4A7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A7→partner) and Y-score (partner→SLC4A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PARD6A →	+0.872	+3.299	.001	.004	3	2
BLOOD_Leukemia	CRACD →	+1.643	+3.199	<.001	.007	3	2
BLOOD_Leukemia	LANCL1 →	+0.726	+3.199	.005	.007	3	2
BLOOD_Leukemia	TAF12 →	+0.420	+3.259	.008	.006	3	2
BLOOD_Leukemia	KDM1A →	+0.680	+3.199	.005	.007	3	2
LARGE_INTESTINE	FZD3 →	+0.938	+3.212	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 630 associations by consensus.

PARD6A by SLC4A7 expression — LARGE_INTESTINE

Explore this box plot interactively →