Across TCGA patient cohorts, SLC4A5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,620 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC4A5-associated genes across cancer lineages are SEC14L2, TTC28, and SLC5A4. Each is linked with SLC4A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A5-to-partner and partner-to-SLC4A5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A5→partner) and Y-score (partner→SLC4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC14L2 →	+2.234	+2.299	<.001	.002	3	1
BRCA	TTC28 →	+0.933	+1.805	<.001	<.001	3	1
BRCA	SLC5A4 →	+0.496	+1.781	.005	<.001	3	1
BRCA	DDX17 →	+1.111	+2.179	<.001	<.001	3	1
BRCA	XBP1 →	+2.969	+2.823	<.001	<.001	3	1
BRCA	TIMP3 →	+1.903	+2.661	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,620 associations by consensus.

Exploration

SLC4A5 survival (RNA) · tumor vs normal (RNA) · all SLC4A5 data types