Across TCGA patient cohorts, SLC4A5 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A5-associated genes across cancer lineages are PCNA, Caspase-7-cleavedD198, and Rad50. Each is linked with SLC4A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC4A5-to-partner and partner-to-SLC4A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A5→partner) and Y-score (partner→SLC4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.181	+1.662	.006	.010	3	4
COAD	Caspase-7-cleavedD198 →	+1.385	+3.186	<.001	.009	3	3
COAD	Rad50 →	-0.342	-3.296	.001	.009	3	2
COAD	RAD51 →	+0.153	+3.467	.031	.002	3	2
COAD	TSC1 →	-0.403	-3.450	.001	.005	3	2
COAD	c-Kit →	-0.807	-3.169	.002	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

SLC4A5 survival (RNA) · tumor vs normal (RNA) · all SLC4A5 data types