Across TCGA cell cohorts, SLC4A5 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC4A5-associated genes across cancer lineages are IL22, CCDC182, and INS. Each is linked with SLC4A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A5-to-partner and partner-to-SLC4A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A5→partner) and Y-score (partner→SLC4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL22 →	+0.021	+4.247	<.001	.004	3	2
OVARY	CCDC182 →	+0.064	+3.700	<.001	.005	3	2
BREAST	INS →	+0.186	+4.199	<.001	.007	3	1
SKIN	OR4X2 →	+0.017	+3.930	.001	.003	3	1
SKIN	OR5T3 →	+0.012	+4.437	<.001	.004	3	1
SKIN	OR52B6 →	+0.040	+3.920	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

SLC4A5 survival (RNA) · tumor vs normal (RNA) · all SLC4A5 data types