SLC4A4

Across TCGA cell cohorts, SLC4A4 mutation is significantly associated with the RNA expression of many other genes, with 318 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC4A4-associated genes across cancer lineages are BANF2, REG3G, and CFAP299. Each is linked with SLC4A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A4-to-partner and partner-to-SLC4A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF2 grouped by SLC4A4-low versus SLC4A4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A4→partner) and Y-score (partner→SLC4A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BANF2 →	+0.096	+5.643	<.001	.002	3	2
BLOOD_Myeloma	REG3G →	+0.049	+4.321	<.001	<.001	3	1
BLOOD_Myeloma	CFAP299 →	+0.111	+3.584	<.001	.007	3	1
BLOOD_Myeloma	PRR23A →	+0.047	+3.285	.003	.009	3	1
KIDNEY	TAS2R8 →	+0.030	+5.000	<.001	.005	3	1
KIDNEY	OR6P1 →	+0.013	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

BANF2 by SLC4A4 expression — BLOOD_Lymphoma

Explore this box plot interactively →