SLC4A2

Across TCGA patient cohorts, SLC4A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SLC4A2-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgA isotypes, Negative regulation of hippo signaling, and XMP metabolic process. Each is linked with SLC4A2 in more than 26 cancer types. Because this analysis shows association rather than direction, both SLC4A2-to-partner and partner-to-SLC4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgA isotypes grouped by SLC4A2-low versus SLC4A2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A2→partner) and Y-score (partner→SLC4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of isotype switching to IgA isotypes →	+0.091	+0.841	<.001	<.001	3	27
CHOL	Negative regulation of hippo signaling →	+0.087	+0.905	<.001	.002	3	27
DLBC	XMP metabolic process →	+0.083	+0.656	<.001	<.001	3	26
DLBC	Centrosome duplication →	+0.058	+0.618	<.001	<.001	3	25
SCLC	Regulation of enamel mineralization →	+1.645	+1.882	<.001	<.001	3	25
SCLC	Positive regulation of enamel mineralization →	+1.453	+1.882	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Positive regulation of isotype switching to IgA isotypes by SLC4A2 expression — DLBC

Explore this box plot interactively →