SLC4A2

Across TCGA patient cohorts, SLC4A2 mutation is significantly associated with the RNA expression of many other genes, with 4,152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A2-associated genes across cancer lineages are RN7SL238P, MIR4797, and RPL23AP90. Each is linked with SLC4A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A2-to-partner and partner-to-SLC4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL238P grouped by SLC4A2-low versus SLC4A2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A2→partner) and Y-score (partner→SLC4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL238P →	+0.055	+5.464	<.001	.001	3	3
ACC	MIR4797 →	+0.621	+4.887	<.001	.009	3	3
UCEC	RPL23AP90 →	+0.211	+1.589	.002	.001	3	3
SKCM	GRPEL1 →	+0.459	+3.328	.004	.005	3	3
SKCM	PSMD9 →	+0.369	+3.353	.007	.005	3	3
LGG	MIR4654 →	+0.447	+5.760	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

RN7SL238P by SLC4A2 expression — BRCA

Explore this box plot interactively →