SLC4A1APP2

Across TCGA pan-cancer cohorts, SLC4A1APP2 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated SLC4A1APP2 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SLC4A1APP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC4A1APP2 expression acts as an unfavorable survival marker.

SKCM, BLCA, and STAD are the cancer types where SLC4A1APP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.228	0.744	<.001	147	view →
BLCA	DFS	Tertile	All	0.128	0.627	<.001	54	view →
STAD	DFS	Tertile	All	0.435	0.724	.006	36	view →
THYM	DFS	Tertile	All	0.075	0.885	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
MESO	DFS	Tertile	All	0.099	0.392	.030	27	view →
CESC	OS	Tertile	II,III,IV	0.094	0.545	.020	18	view →
LGG	DFS	Tertile	All	0.493	0.847	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

SLC4A1APP2–SKCM (DFS)

Open the SKCM breakdown →