SLC4A1

Across TCGA patient cohorts, SLC4A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,906 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC4A1-associated GO terms across cancer lineages are Positive regulation of DNA repair, Nitric oxide transport, and Protein dephosphorylation. Each is linked with SLC4A1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC4A1-to-partner and partner-to-SLC4A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by SLC4A1-low versus SLC4A1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A1→partner) and Y-score (partner→SLC4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of DNA repair →	+0.074	+0.349	<.001	<.001	3	17
LAML	Nitric oxide transport →	+0.261	+3.010	<.001	<.001	3	16
STAD	Protein dephosphorylation →	+0.067	+0.183	<.001	<.001	3	16
STAD	Negative regulation of kinase activity →	+0.060	+0.188	<.001	<.001	3	15
STAD	Adaptive thermogenesis →	+0.051	+0.213	<.001	<.001	3	14
STAD	Cytokinesis →	+0.065	+0.140	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,906 associations by consensus.

Positive regulation of DNA repair by SLC4A1 expression — SCLC

Explore this box plot interactively →