SLC4A1

Across TCGA patient cohorts, SLC4A1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A1-associated genes across cancer lineages are HBA2, HBA1, and HBB. Each is linked with SLC4A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC4A1-to-partner and partner-to-SLC4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC4A1 versus HBA2 in PDAC, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A1→partner) and Y-score (partner→SLC4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBA2 →	+2.461	+1.163	<.001	<.001	3	10
GBM	HBA1 →	+1.848	+1.107	<.001	<.001	3	10
PDAC	HBB →	+2.686	+1.115	<.001	<.001	3	10
GBM	PF4 →	+0.943	+0.872	<.001	<.001	3	8
PDAC	PPBP →	+1.233	+0.811	<.001	.001	3	7
OV	FOS →	+1.473	+0.842	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,764 associations by consensus.

SLC4A1 vs HBA2 — PDAC

Explore this scatter interactively →