SLC4A1

Across TCGA cell cohorts, SLC4A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,328 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC4A1-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Positive regulation of monoatomic ion transmembrane transport, and Positive regulation of monoatomic ion transport. Each is linked with SLC4A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLC4A1-to-partner and partner-to-SLC4A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by SLC4A1-low versus SLC4A1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A1→partner) and Y-score (partner→SLC4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of gene expression, epigenetic →	+0.059	+0.029	<.001	.008	2	8
LARGE_INTESTINE	Positive regulation of monoatomic ion transmembrane transport →	-0.077	-0.022	.001	.007	3	6
KIDNEY	Positive regulation of monoatomic ion transport →	-0.072	-0.085	<.001	.009	3	6
LARGE_INTESTINE	Actin-mediated cell contraction →	-0.085	-0.033	<.001	<.001	3	6
STOMACH	Heterochromatin formation →	+0.075	+0.049	<.001	<.001	3	6
STOMACH	Epigenetic regulation of gene expression →	+0.070	+0.049	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,328 associations by consensus.

Negative regulation of gene expression, epigenetic by SLC4A1 expression — STOMACH

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