Across TCGA patient cohorts, SLC48A1 mutation is significantly associated with the RNA expression of many other genes, with 120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC48A1-associated genes across cancer lineages are RN7SL542P, UHRF1, and CSPG4P1Y. Each is linked with SLC48A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC48A1-to-partner and partner-to-SLC48A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC48A1→partner) and Y-score (partner→SLC48A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL542P →	+0.097	+3.226	.005	.005	3	2
UCEC	UHRF1 →	+0.819	+2.711	.005	.003	3	1
BRCA	CSPG4P1Y →	+0.044	+9.057	<.001	.003	3	1
UCEC	FANCA →	+0.608	+2.700	.003	.006	3	1
UCEC	LONP1 →	+0.724	+3.386	<.001	.004	3	1
UCEC	MT-ND2 →	-0.838	-3.796	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

Exploration

SLC48A1 survival (RNA) · tumor vs normal (RNA) · all SLC48A1 data types