SLC47A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC47A2 mutation is significantly associated with the RNA expression of many other genes, with 1,253 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC47A2-associated genes across cancer lineages are DBF4P3, MTND3P9, and EIF1P4. Each is linked with SLC47A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC47A2-to-partner and partner-to-SLC47A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DBF4P3 grouped by SLC47A2-low versus SLC47A2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC47A2→partner) and Y-score (partner→SLC47A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADDBF4P3 →+0.082+5.044.005.00933
COADMTND3P9 →+0.207+4.392<.001.00632
COADEIF1P4 →+0.860+3.841<.001.00532
COADMIR3648-2 →+0.259+4.547<.001.00532
SKCMDHODH →+0.514+3.366.002.00532
HNSCRN7SKP76 →+0.140+5.912<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,253 associations by consensus.

DBF4P3 by SLC47A2 expression — LUAD

Box plot of DBF4P3 in SLC47A2-low vs SLC47A2-high samples in LUAD.

Explore this box plot interactively →

Exploration