SLC47A2

Across TCGA cell cohorts, SLC47A2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC47A2-associated genes across cancer lineages are FMO1, SEMG2, and CPLX4. Each is linked with SLC47A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC47A2-to-partner and partner-to-SLC47A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FMO1 grouped by SLC47A2-low versus SLC47A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC47A2→partner) and Y-score (partner→SLC47A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FMO1 →	+0.111	+3.658	<.001	.005	3	1
LARGE_INTESTINE	SEMG2 →	+0.706	+3.878	<.001	.003	3	1
LARGE_INTESTINE	CPLX4 →	+0.027	+4.807	<.001	<.001	3	1
LARGE_INTESTINE	FAM9B →	+0.443	+3.758	.003	.004	3	1
LARGE_INTESTINE	TFDP3 →	+0.025	+3.196	<.001	.007	3	1
LARGE_INTESTINE	MINAR2 →	+0.040	+3.882	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

FMO1 by SLC47A2 expression — LARGE_INTESTINE

Explore this box plot interactively →