SLC47A1

Across TCGA pan-cancer cohorts, SLC47A1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC47A1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC47A1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC47A1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where SLC47A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.811	0.471	.003	52	view →
GBM	DFS	Quartile	All	0.318	0.942	.038	9	view →
LUAD	DFS	Tertile	II,III,IV	1.000	0.355	.019	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC47A1–CCRCC (OS)

Open the CCRCC breakdown →