SLC47A1

Across TCGA patient cohorts, SLC47A1 mutation is significantly associated with the RNA expression of many other genes, with 825 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC47A1-associated genes across cancer lineages are MYO19, LRRC59, and HSPA9. Each is linked with SLC47A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC47A1-to-partner and partner-to-SLC47A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYO19 grouped by SLC47A1-low versus SLC47A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC47A1→partner) and Y-score (partner→SLC47A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO19 →	+0.396	+2.180	.007	.008	3	3
UCEC	LRRC59 →	+0.457	+3.008	.003	<.001	3	3
UCEC	HSPA9 →	+0.434	+2.526	.003	.001	3	3
UCEC	DNAJC8 →	+0.320	+2.823	.007	.001	3	3
UCEC	EIF2S1 →	+0.530	+2.447	.001	.001	3	3
UCEC	HAUS2 →	+0.552	+2.008	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 825 associations by consensus.

MYO19 by SLC47A1 expression — UCEC

Explore this box plot interactively →