SLC47A1

Across TCGA patient cohorts, SLC47A1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC47A1-associated genes across cancer lineages are ATM, Rab11, and Caspase-7-cleavedD198. Each is linked with SLC47A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC47A1-to-partner and partner-to-SLC47A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC47A1-low versus SLC47A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC47A1→partner) and Y-score (partner→SLC47A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.506	-2.584	.005	.010	3	3
UCEC	Rab11 →	-0.131	-1.980	.024	.030	3	2
UCEC	Caspase-7-cleavedD198 →	+0.581	+1.906	.014	.016	3	2
UCEC	Caspase-8 →	-0.285	-3.087	.004	<.001	3	2
UCEC	eIF4E →	+0.183	+3.183	.030	.009	3	1
UCEC	IGFBP2 →	-0.691	-1.906	.008	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ATM by SLC47A1 expression — UCEC

Explore this box plot interactively →