SLC46A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC46A2 mutation is significantly associated with the RNA expression of many other genes, with 1,204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC46A2-associated genes across cancer lineages are SNORA3C, UBE2V1P6, and RN7SL478P. Each is linked with SLC46A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC46A2-to-partner and partner-to-SLC46A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA3C grouped by SLC46A2-low versus SLC46A2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC46A2→partner) and Y-score (partner→SLC46A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCSNORA3C →+0.327+6.305<.001.00132
LIHCUBE2V1P6 →+0.111+6.676<.001<.00132
UCECRN7SL478P →+0.296+2.161<.001.00532
BLCASNORA10B →+0.339+3.472.002.00332
UCECMIR513B →+0.312+3.162<.001.00132
CESCRNU6-752P →+0.460+7.584<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,204 associations by consensus.

SNORA3C by SLC46A2 expression — LIHC

Box plot of SNORA3C in SLC46A2-low vs SLC46A2-high samples in LIHC.

Explore this box plot interactively →

Exploration