SLC46A1

Across TCGA patient cohorts, SLC46A1 mutation is significantly associated with the RNA expression of many other genes, with 372 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC46A1-associated genes across cancer lineages are RNU1-62P, MIR4530, and RN7SKP268. Each is linked with SLC46A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC46A1-to-partner and partner-to-SLC46A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by SLC46A1-low versus SLC46A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC46A1→partner) and Y-score (partner→SLC46A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-62P →	+0.261	+5.539	<.001	.004	3	2
UCEC	MIR4530 →	+0.482	+1.991	.003	.008	3	2
LIHC	RN7SKP268 →	+0.208	+5.758	<.001	.003	3	2
LIHC	RNU6-1198P →	+0.895	+5.758	<.001	.003	3	1
LIHC	MIR4771-2 →	+0.823	+5.186	<.001	.007	3	1
UCEC	CRYBB2P1 →	+0.512	+3.467	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 372 associations by consensus.

RNU1-62P by SLC46A1 expression — CESC

Explore this box plot interactively →