SLC46A1

Across TCGA cell cohorts, SLC46A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,709 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC46A1-associated GO terms across cancer lineages are Folic acid transport, Regulation of syncytium formation by plasma membrane fusion, and Folate import across plasma membrane. Each is linked with SLC46A1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC46A1-to-partner and partner-to-SLC46A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Folic acid transport grouped by SLC46A1-low versus SLC46A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC46A1→partner) and Y-score (partner→SLC46A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Folic acid transport →	+0.253	+1.603	<.001	<.001	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.120	+1.188	.002	.004	3	13
LUNG_SCLC	Folate import across plasma membrane →	+0.767	+0.971	.003	<.001	3	12
BREAST	Folate transmembrane transport →	+0.172	+1.221	<.001	<.001	3	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+1.202	.007	.003	1	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.096	+0.720	.001	.006	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,709 associations by consensus.

Folic acid transport by SLC46A1 expression — LIVER

Explore this box plot interactively →