SLC45A3

Across TCGA patient cohorts, SLC45A3 mutation is significantly associated with the RNA expression of many other genes, with 2,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC45A3-associated genes across cancer lineages are SNORD116-19, OR1AC1P, and RNU6-211P. Each is linked with SLC45A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC45A3-to-partner and partner-to-SLC45A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-19 grouped by SLC45A3-low versus SLC45A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A3→partner) and Y-score (partner→SLC45A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD116-19 →	+0.390	+1.709	.006	.001	3	3
BLCA	OR1AC1P →	+0.204	+4.122	.001	.008	3	3
CESC	RNU6-211P →	+0.235	+4.342	<.001	.007	3	2
CESC	TRAJ30 →	+0.591	+4.103	<.001	.002	3	2
UCEC	SRCIN1 →	-0.730	-3.159	<.001	<.001	3	2
UCEC	MTUS2-AS1 →	+0.203	+2.025	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,202 associations by consensus.

SNORD116-19 by SLC45A3 expression — UCEC

Explore this box plot interactively →