SLC45A3

Across TCGA cell cohorts, SLC45A3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC45A3-associated genes across cancer lineages are CD300H, C20orf85, and ST8SIA2. Each is linked with SLC45A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC45A3-to-partner and partner-to-SLC45A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by SLC45A3-low versus SLC45A3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A3→partner) and Y-score (partner→SLC45A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.027	+3.678	<.001	.001	3	1
BLOOD_Leukemia	C20orf85 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	ST8SIA2 →	+0.574	+3.906	.002	.003	3	1
BLOOD_Leukemia	MYOCD →	+0.917	+4.523	<.001	.001	3	1
BLOOD_Leukemia	NPFFR1 →	+0.010	+4.359	.002	<.001	3	1
BLOOD_Leukemia	FAM83B →	+0.117	+3.234	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CD300H by SLC45A3 expression — LARGE_INTESTINE

Explore this box plot interactively →