SLC45A3

Across TCGA cell cohorts, SLC45A3 mutation is significantly associated with the mutation status of many other genes, with 5,324 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC45A3-associated genes across cancer lineages are EPB41, GRIK3, and RASAL1. Each is linked with SLC45A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC45A3-to-partner and partner-to-SLC45A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPB41 grouped by SLC45A3-low versus SLC45A3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A3→partner) and Y-score (partner→SLC45A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	EPB41 →	+5.584	+5.014	.003	.003	1	4
SKIN	GRIK3 →	+2.807	+4.247	.007	.007	1	4
LARGE_INTESTINE	RASAL1 →	+4.584	+3.350	.003	.003	1	4
SKIN	PLAGL2 →	+4.392	+4.392	.009	.009	1	4
LARGE_INTESTINE	KIRREL3 →	+3.584	+3.007	.008	.008	1	4
SKIN	CDK13 →	+3.169	+4.548	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,324 associations by consensus.

EPB41 by SLC45A3 expression — BLOOD_Lymphoma

Explore this box plot interactively →