SLC45A2

Across TCGA patient cohorts, SLC45A2 mutation is significantly associated with the RNA expression of many other genes, with 2,443 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC45A2-associated genes across cancer lineages are HSPD1P18, DHX33-DT, and STIP1. Each is linked with SLC45A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC45A2-to-partner and partner-to-SLC45A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPD1P18 grouped by SLC45A2-low versus SLC45A2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A2→partner) and Y-score (partner→SLC45A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HSPD1P18 →	+0.267	+2.963	<.001	.005	3	3
STAD	DHX33-DT →	+0.254	+3.867	<.001	.004	3	3
UCEC	STIP1 →	+0.421	+1.893	<.001	<.001	3	3
UCEC	CCL5 →	+0.959	+1.914	<.001	<.001	3	2
UCEC	IGHV2-70 →	+1.369	+2.485	<.001	<.001	3	2
BRCA	OR5J7P →	+0.094	+6.882	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,443 associations by consensus.

HSPD1P18 by SLC45A2 expression — COAD

Explore this box plot interactively →