SLC45A2

Across TCGA patient cohorts, SLC45A2 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC45A2-associated genes across cancer lineages are ATM, PRDX1, and TIGAR. Each is linked with SLC45A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC45A2-to-partner and partner-to-SLC45A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC45A2-low versus SLC45A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A2→partner) and Y-score (partner→SLC45A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.623	-2.137	<.001	.001	3	4
COAD	PRDX1 →	+0.413	+2.824	<.001	.034	3	3
UCEC	TIGAR →	+0.114	+1.274	.028	.028	3	2
COAD	GAPDH →	+1.013	+2.820	<.001	.035	3	2
COAD	4E-BP1_pT70 →	+0.142	+2.815	.031	.036	3	2
LUAD	p27_pT198 →	+0.183	+2.824	.005	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

ATM by SLC45A2 expression — UCEC

Explore this box plot interactively →