SLC45A2

Across TCGA cell cohorts, SLC45A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,127 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC45A2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with SLC45A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC45A2-to-partner and partner-to-SLC45A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SLC45A2-low versus SLC45A2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A2→partner) and Y-score (partner→SLC45A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of myoblast fusion →	+0.135	+0.227	<.001	.001	3	7
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.076	+0.126	<.001	.002	3	7
PANCREAS	Regulation of myoblast fusion →	+0.060	+0.072	.002	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Protein modification by small protein removal →	+0.045	+0.166	.003	.004	3	6
SKIN	Melanin biosynthetic process from tyrosine →	+1.642	+5.904	<.001	<.001	3	6
SKIN	Cytosolic transport →	+0.052	+3.328	.006	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,127 associations by consensus.

Negative regulation of myoblast fusion by SLC45A2 expression — BONE

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